Our state-of-the art amenities facilitate our world-class research
Our cutting-edge drug and vaccine discovery and development resources are also available to external research groups and industry.
Explore our facilities and resources below, and if you’d like more information on any of our services, please get in touch.
Recently established within the Institute for Glycomics, the ZymeBank facility provides enzymes that support both internal and external research projects. By cloning into various mammalian or bacterial expression vectors, ZymeBank is able to produce enzymes essential for glycan synthesis in high quality and purity. Activity assays have been developed to allow for in-depth characterisation of enzyme functions which guides enzyme use in downstream applications such as chemo-enzymatic synthesis. Currently, a range of human and bacterial sialyltransferases and fucosyltransferases have been expressed and characterised. Enzymes for sugar-nucleotide biosynthesis and nucleotide triphosphate regeneration are also available. We currently have nearly 30 enzymes in stock, and this number is growing rapidly. ZymeBank also provides technical support in molecular cloning, expression, purification, and assay development.
- ready to use enzymes
- expression plasmids (in-house cloned)
- molecular cloning
- protein expression and purification
- assay development
Computational chemistry and visualisation
Nuclear magnetic resonance spectroscopy
Protein X-ray crystallography
Advanced microscopy and imaging
PC2, PC3 and GMP-compliant laboratories
In vivo models
We have in-house access to a range of in vivo models and a substantial, fully staffed facility, including PC2 and PC3 suites. We also have animal models for autoimmune inflammatory diseases.
Clinical samples and cell lines
We have a growing number of clinical samples and novel cell-lines relevant to infectious diseases and cancer research.