Translating research into tangible benefits
The term translational research is often used interchangeably with translational medicine, or translational science, or bench to bedside. It involves building on basic scientific research to create new diagnostics, drugs or vaccines in the fight against disease. The term translational refers to the "translation" of basic scientific findings in a laboratory setting into potential solutions for disease.
Our researchers identify opportunities that can lead to new diagnostics, drugs and vaccines, translating research into tangible benefits for the global community.
Translational research may lead to a better understanding of disease or identify new ways to treat, prevent or diagnose disease to enhance human health and wellbeing. This involves applying laboratory-based discoveries to clinical studies (bench to bedside) and can ultimately result in the production of a new treatment/diagnostic test which can be used in clinical and community settings. It can often take many years for a laboratory discovery to be tested and if found effective, applied into healthcare settings. From the laboratory bench to the patient’s bedside, translational outcomes are the ultimate goal of the Institute for Glycomics. With a track record of taking technologies to market and leadership focused on translational science, we have no doubt that we will be successful in discovering and developing the next generation of biomedical solutions.
Critical to delivering blockbuster technologies are two key factors:
- Providing outstanding infrastructure
- Assembling the brightest scientific minds through strategic appointments of research leaders of international standing, who demonstrate excellence in fundamental science while delivering commercial outcomes through translational science.
OUR RESEARCH PROVIDES NEW HOPE FOR TREATMENT OF HAND, FOOT AND MOUTH DISEASE
A new scientific discovery, thanks to one of the research groups at the Institute for Glycomics, is providing new hope for the development of an effective treatment of Hand, Foot and Mouth Disease.
HOPE FOR NEW BLOOD TEST TO DETECT EARLY STAGE OVARIAN CANCER
Research on a bacterial toxin has led to the development a new blood test for the potential early diagnosis of ovarian cancer.
From the laboratory bench to the patient’s bedside, translational outcomes are the ultimate goal of the Institute for Glycomics.
Mark von Itzstein AO
Phase III clinical trial
Examines the effectiveness of the intervention in larger groups of volunteers (several hundred to several thousand) by comparing it with no treatment or with other standard or experimental treatments. Side effects are also examined to gather additional safety information in a larger group of people.
Phase IV clinical trial
These are normally conducted after the intervention has been marketed. These studies monitor the effectiveness of the intervention in the general population and continue to collect information about side effects over a longer period of time. If the new intervention/diagnostic test performs well in Clinical Trials, it needs to be approved by the government before it is available for use in the general population. In Australia, new interventions and treatments are approved by the Therapeutic Goods Administration.