Developing disruptive technologies to prevent and manage various neuromusculoskeletal and cardiovascular conditions

GCORE researchers are passionate about innovation, research and education across the ‘lifecycle’ of musculoskeletal, neurological, cardiac and vascular conditions. Our people represent members of Griffith University, the Gold Coast University Hospital and other hospitals on the Gold Coast and Brisbane. We undertake research and development in cross-disciplinary groups spanning various areas of biomedical and rehabilitation science, design and engineering. The success of our projects is demonstrated by the creation of commercialised medical technologies and health solutions that demonstrably improve public health, enable personalised therapies and reduce health care costs.

The vision

GCORE’s vision is to impact the health industry through disruptive multiscale solutions. We are building a global reputation in biomedical and rehabilitation engineering research and development. We are doing this by training the next generation of clinicians and medical staff in the use of innovative technologies to manage their patient's health conditions and rehabilitation therapies. We also promote knowledge and skills exchange through our strong collaboration with hospitals and industry.

Our mission is:

  • To collaboratively discover and develop innovative technologies engaging multiscale mechanobiological and biophysical processes.
  • To inform and influence health regulators on the benefits and value of these technologies and to work with clinical and industry partners to drive their adoption.
  • To enable industry partners to test, trial and commercialise technologies that advance our vision and support the transformation of the musculoskeletal, neurological, cardiac and vascular fields.

GCORE’s direction is overseen by an Advisory Board that embraces collaboration between researchers, engineers, clinicians, professionals, industry and institutional partnerships within Australia.

Research areas

Multiscale human biophysics

Using advanced medical imaging, motion capture, wearables and ‘Personalised Digital Twin’ models, we explore cells, tissues, organs and the whole body to understand their dynamic function. We determine the causes of tissue degeneration and organ dysfunction to inform innovative therapies that prevent, slow or reverse disease.

Optimised therapies using modelling and simulation

Using advanced medical imaging and ‘Personalised Digital Twin’ models, we perform virtual therapy planning and simulate outcomes to inform therapy. From these we also generate 3D printed functional anatomical models to plan clinical interventions and train clinicians.

Development of medical and assistive devices

Using advanced medical imaging, wearables and ‘Personalised Digital Twin’ models, we design and 3D print medical, assistive and rehabilitation devices to account for the complex, non-linear and dynamic interaction between the human and engineering devices.

Tissue engineering and regenerative medicine

We develop, design, trial and use 3D printed biological and engineered constructs to repair tissues such as tendons and ligaments.

Wearables

We develop wearable technologies to optimise the performance of athletes and enable research into the causes of and recovery from injuries and disease. We develop our devices to be effective for injury prevention, training and rehabilitation programs.

Facilities

ADAPT 1.0

ADaPT's high-tech mechanical testing and additive manufacturing capabilities enable us to develop orthopaedic implants and wearable devices. These include a range of software suites, industry standard multi-disciplinary collaboration space with high-end multiprocessor workstations linked into the Griffith’s high performance-computing cluster, a 6-degree of freedom robotic machine for testing orthopaedic implants and mock circulatory system for testing cardiovascular devices, 3D multi-metal printer (Renishaw AM400), plus a range of polymer, carbon fibre and biological printers, exceeding 50 different 3D printers in total.

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EXERCISE SCIENCE & SPORT

Griffith's biomechanics facilities support our research into musculoskeletal and orthopaedic conditions. We have access to two motion capture laboratories, instrumented treadmills, force platforms, wireless EMG and IMU systems, pQCT, DXA, 2D, 3D and elastography ultrasound systems, isokinetic dynamometers, and computational and medical image processing software.

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INDUSTRY

Strong collaborative links with QScan and Philips Healthcare entails us direct access to Philips’ Australasian reference MRI scanners and software at QScan, as well as direct support from Philips’ Australian Clinical MRI Scientist, Dr Iain Ball, and QScan’s chief MRI technologist, Mr Ben Kennedy.

We have full access to 3D clinical gait analysis facilities and research time on various medical imaging machines (MRI, CT) as a result of our collaboration with various hospitals, including Brisbane Childrens’ Hospital, Gold Coast University Hospital, Sydney Children’s Hospital, and Gold Coast Private Hospital.

Work with us

GCORE works with leading industry partners to develop and design health care solutions across the lifecycle of musculoskeletal, neurological, cardiac and vascular conditions.

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Our researchers

Professor David Lloyd

David Lloyd is the Director of GCORE and co-founder of ADaPT. A mechanical engineer from the aeronautical industry, he has a PhD and postdoctoral training in computational biomechanical engineering and neurophysiology. David is an international leader in these fields, ranked the 2019 Australian field leader in Biophysics and recipient of the 2020 International Geoffrey Dyson award.

Professor Randy Bindra

Professor Bindra is an Orthopaedic Surgeon specializing in surgery of the hand, wrist and peripheral nerve for all age groups, including paediatrics. Professor Bindra has received international training at the University of Mumbai, India, University of Liverpool, UK and Washington University in St Louis, USA. He holds Fellowship at several international institutions and currently serves as Secretary of Queensland Hand Surgery Society.

Professor Rod Barrett

Professor Barrett has published over 100 international refereed journal articles in Musculoskeletal Biomechanics. His ongoing research is focused on the use of medical imaging and computational methods to prevent and/or better manage musculoskeletal conditions including tendinopathy and lower limb osteoarthritis.

Professor Michel Coppieters

Professor Coppieters is a researcher of musculoskeletal physiotherapy. He has a longstanding interest in neuropathic pain and continues to lecture and research the neurobiology of pain and the clinical diagnosis and management of patients with neuropathies.

Professor Mark Forwood

Professor Forwood is Foundation Chair of Anatomy at Griffith. He has contributed substantially to understanding the biology of skeletal adaptation, stress fracture repair and bone tissue quality in osteoarthritis, osteoporosis and tissue banking. His laboratory has expertise in orthopaedic biomechanics, fatigue microdamage analysis, histology and dynamic bone histomorphometry.

Professor Geoff Tansley

Professor Tansley is a mechanical and biomedical engineer with broad experience in the medical devices and manufacturing industries. He consults widely to medical device companies. His has long held advanced specialisation in the mechanics of Couette blood flow, and more broadly cardiac and vascular medical device design and fluid dynamics. He has worked in and has extensive experience in the cardiac and vascular assistive device industry.

A/Prof Chris Carty

A/Prof Carty is an exercise physiologist and clinical biomechanist with leadership roles in healthcare and clinical research. His contributions to medical research and clinical service delivery have focused on the application of engineering principles in the clinical management of the lifespan of patients with movement disorders. His current research interests include 3D printing and predictive modelling to inform paediatric deformity correction surgery.

Dr Matthew Barton

Dr Matthew Barton completed his PhD in 2015 on "Peripheral nerve repair” and has significant experience in designing and testing novel biomaterial approaches for peripheral nerve repair and regeneration, and has further expertise in the neuroanatomy of peripheral nerves.

Dr Martina Barzan

Dr Barzan is a bioengineer skilled in neuromusculoskeletal biomechanics, gait analysis, medical imaging, 3D CAD design, orthopaedic surgery and implant design optimisation and additive manufacturing. She works on orthopaedic biomechanics and is currently developing personalised digital twins of children with hip deformities. She completed a PhD on the development of personalised knee kinematic models of children with recurrent patellar dislocation

Dr Matthew Bourne

Dr Bourne is an Early Career Researcher and Lecturer in the School of Allied Health Sciences and Menzies Health Institute Queensland at Griffith University, and an Adjunct Researcher at La Trobe University’s Sport and Exercise Medicine Research Centre in Melbourne. Dr Bourne’s overarching research mission is to conduct world-class, multidisciplinary research in sport and exercise medicine, which has direct implications for improving clinical practice. He is primarily interested in the application of targeted exercise to prevent injury and enhance performance.

Dr Sam Canning

Dr Canning is a lecturer in Digital Media and Industrial Design interested in the fusion of traditional craft knowledge with new technologies. Sam trained as a French Polisher specialising in antique restoration and during this time developed an interest in CNC machining and its potential for craft practice. He then studied Industrial Design at QUT and gained his PhD in 3D printing from the Queensland College of Art. Sam has vast expertise in the industrial design of medical devices and other industrial commercial products for which has been the recipient of Australian Design awards.

Dr Brooke Coombes

Dr Coombes has two main areas of research - understanding the adaptation of the musculotendinous system to ageing, obesity, injury and rehabilitation and understanding the impact of chronic pain on quality of life and physical activity in people with diabetes. Brooke has lead clinical trials to investigate the efficacy of interventions for tendinopathy and developed innovative imaging techniques to non-invasively quantify tissue mechanical properties

Dr Laura Diamond

Dr Laura Diamond is a biomedical engineer and early career researcher who integrates a unique blend of skills in engineering and clinical sciences to understand the neuromuscular and biomechanical mechanisms that underlie the pre- and early-arthritic hip.

Dr Steven Duhig

Dr Steven Duhig completed his PhD in 2017 on “hamstring string injuries”. His research is focussed on how muscle architecture influences function then using this information to better inform injury prevention strategies.

Dr Stephen Hamlet

Dr Hamlet is a Senior Research Fellow in the School of Dentistry and Oral Health. His research interests include bone regeneration, diseases of the jaw and 3D modelling to optimise cancer therapy delivery. He holds a PhD from Griffith.

Dr Gavin Lenton

Gavin specialises in computational models of the lower limb joints and has applied these models to characterise lower-limb joint loading and energetics during military load carriage. Gavin works conjointly with VALD Performance. More recently, his research is focused on extending novel methods for real-time assessment of joint loading, and creating personalised, digital representations of our musculoskeletal systems and wearable devices.

Dr Dinesh Palipana

Dr Palipana is a resident medical officer at the Gold Coast University Hospital, Griffith lecturer and adjunct research fellow with Menzies Health Institute Queensland. He earned a Bachelor of Laws prior to completing his Doctor of Medicine at Griffith. He has a cervical spinal cord injury and is such an advocate for inclusivity in medicine and the workplace. He is a founding member of Doctors with Disabilities Australia.

Dr Nataliya Perevoshchikova

Dr Perevoshchikova is an early career materials scientist and engineer specialising in advanced design of musculoskeletal implants. She holds a PhD in Material Science and Engineering. Nataliya uses advanced computational methods to refine implant design and positioning in the human body, and has expertise in optimisation of additive manufacturing processes for titanium.

Dr Claudio Pizzolato

Dr Claudio Pizzolato is a postdoctoral research fellow and mechatronic engineer focused on creating real-time digital twins to understand the effect of human movement on musculoskeletal tissue. Applications of his research involve advanced rehabilitation, sensory augmentation, and injury prevention.

Dr David Saxby

Dr Saxby holds a PhD in computational neuromuscular biomechanics. His research focus is modelling the loading and response of articular tissues. He is engaged in projects with clinical (e.g., osteoarthritis and ligament injury), sport (e.g., hamstring injury), and military applications.

Dr Michael Simmonds

Dr Simmonds is an inspirational young researcher who received Young Tall Poppy (2018) and Flying Scientist (2019-2020) awards in recognition of his achievements in research and science communications. A blood physiologist, Michael works closely with mechanical engineers, medical doctors, and scientific bodies to explore how the artificial materials and high mechanical forces employed within cardiac assistive devices change blood cells structure and function.

Mr Derek Smith

Derek is Technical Manager in Griffith’s Advanced Design and Prototyping Technologies Institute. He is a mechanical engineer that has long experience in the design and manufacture of biomedical implants. Derek has held positions in many medical device companies, including mechanical design team leader at Cochlear. He has extensive specialisation in the design and optimal use of additive manufacturing in the medical and other industries.

Dr Antony McNamee

Antony is a postdoctoral scientist in Griffith's Mechanobiology Laboratory and a biophysics lecturer. His research focuses on the blood rheology and the mechanobiology of erythrocytes, with an emphasis on the changes induced by mechanical stimuli following exposure to high shear environments representative of mechanical circulatory assist devices and artificial organs.

Dr Jayishni Maharaj

Jayishni is a Postdoctoral Research Fellow working at the intersection of biomechanics, rehabilitative and computer science. Her work explores the relationship between structure, function and injury in the foot. Jayishni holds a Phd in Biomechanics and Motor Control.

Want to know more?

Contact the Menzies Health Institute Queensland for more information