NCNED is a world-class research facility focusing on the etiology and pathomechanisms of ME/CFS. Our research is focused towards identifying biomarkers of ME/CFS for translation into the clinical environment.
NCNED is the first to report in CFS:
- a reduction in white matter in the brainstem and a compensatory increase in white matter in the cortex – the action part of the brain;
- raised activity in critical brain regions but decreased communication between them resulting in recruitment of more brain regions to perform a cognitive task;
- correlation between the information potential in brain activity and measures of physical and mental wellbeing.
Our focus now is to investigate differences in brainstem function in CFS, in particular within an important network of small centres in the brainstem called the reticular activation system. This system influences arousal levels of the brain as a whole, the sleep-wake cycle, learning, memory and problem solving.
A discussion with the Co-Directors
CFS/ME International Conference RID 2018 Presentations
- CFS/ME International Conference: Research Innovation and Discovery
- National Institutes of Health Support of Research on ME/CFS
- Leveraging philanthropy and community to create social change
- Whole-body cryotherapy (QBC) - a potential non-pharmacological allied treatment for CFS/ME
- Provocation Testing in CFS/ME
- Brain stem myelination and MRI changes in CFS/ME
- Planning and implementation of longitudinal cohort studies: opportunities, pitfalls and rewards
NOTE: 2021 ME/CFS International RID Conference 16-17 November (Gold Coast)