Cancer – New approach for brain tumour sufferers
Brain tumours are one of the most aggressive forms of cancer. Research led by Professor Sally-Ann Poulsen may offer new hope to combat this disease by altering the environment that enables brain cancer cells to resist current chemotherapy drugs.
By working with already approved chemotherapy drugs, the team expects that the length of time to reach the market may be shortened for potential drugs identified by this approach. The research was at the stage of early discovery and preclinical testing in late 2016.Read more
Cancer – innovative technologies for new treatments - Avery Group Drug Discovery
With cancer a leading cause of death in Australia, there are few families today that are unaffected by the disease. Members of the GRIDD team led by Professor Vicky Avery are using a range of approaches to find new treatments for many types of cancers including breast, prostate, pancreatic and ovarian.
Utilising innovative technologies incorporating 3D culturing techniques and high throughput, high content imaging, her team addresses fundamental questions regarding the roles different cells play in the tumour microenvironment and how this relates to metastasis and drug resistance.
By exploiting this new knowledge and their technical expertise, her team hopes to design improved chemotherapeutics to overcome limitations of many drugs used today, and provide therapeutics for cancers for which there are simply no current treatment options.Read more
Collaboration with the Translational Research Institute (TRI)
Collaboration is the name of the game for GRIDD’s natural products chemist, Associate Professor Rohan Davis who has been working primarily on prostate cancer research with Australia’s TRI since 2012. In a significant step forward, the Davis team has recently identified compounds with unique mechanisms of action.
In addition to his research, Rohan particularly enjoys a key part of his GRIDD role, the supervising of talented PhD students. He notes that training at the Institute is excellent, and most of the students find positions overseas once they have completed their doctorates.Read more