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Home > Professional page > Dr Derek Kennedy > Publications

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  • Dr Derek Kennedy
  • Curriculum vitae
  • Publications

Journal Articles

  1. Berruti, A.; Generali, D.; Kaufmann, M.; Puztai, L.; Curigliano, G.; Aglietta, M.; Gianni, L.; Miller, WR.; Untch, M.; Sotiriou, C.; Daidone, MG.; Conte, P.; Kennedy, D.; Damia, G.; Petronini, PG.; di Cosimo, S.; Bruzzi , P.; Dowsett, M.; Desmedet, C.; Mansel, RE.; Marsoni, S.; Olivetti, L., Tondini, C.; Sapino, A., Fenaroli, P.; Tortora, GP.; Thorne, H.; Bertolini, F.; Ferrozzi, F.; Danova, N.; Tagliabue, E.; da Azambuja, E.; Makris, A.; Tampellini, M.; Dontu, G.; Van’t Veer, L.; Harris, AL.; Fox, SB.; Dogliotti, L.; Bottini, A. (accepted) International expert consensus on primary systemic therapy in the management of earlybreast cancer. Highlights of the third symposium on primary systemic therapy in the management of operable breast cancer, Cremona. Italy, 2010. Journal of the National Cancer Institute Accepted
  2. Ahmadabadi, B.; Hassanshahi, G.; Arababadi, MK.; Leanza, C.; Kennedy, D. (accepted, proof available 2011). The IL-10 promoter polymorphism at position -592 is correlated with susceptibility to occult HBV infection. Inflammation Accepted
  3. Arababadi, MK.; Ahmadabadi, BN.; Salehabadi, VA.; Kennedy, D. (accepted). Interleukin (IL)-10 gene polymorphisms is associated with type 2 diabetic patients with nephropathy. Inflammation Accepted
  4. Arababadi, MK.; Hassanshahi, G.; Ahmadabadi, BN.; Hakimi, H.; Rezaeian, M.; Salehabadi, VA.; Yousefidaredor, H.; Abousaidi, H.; Kennedy, D. (In press). Association of -592 region of IL-10 polymorphisms with asthma in south-eastern Iranian patients. Clinical Laboratory In Press
  5. Arababadi, MK.; Aminzadeh, F.; Hassanshahi, G.; Khorramdelazad, H.; Norouzi, M.; Zarandi, ER.; Rezayati, M.; Kennedy, D. (In press). Association of IL-6 and IL-12, but not IL-10 with pre-term neonate births. LabMedicine In Press
  6. Assar, S.; Arababadi, MK.; Mohit, M.; Ahmadabadi, BN.; Pumpens, P.; Khorramdelazad, H.; Hajghani, M.; Araste, M.; Nekhei, Z.; Sendi, H.; Kennedy, D. (In Press) T helper and B cell escape mutations within the HBc gene in patients with asymptomatic HBV infection: a study from the South-Eastern region of Iran. Clinical Laboratory. In Press
  7. Arababadi, MK.; Pourfathollah, AA.; Jafarzadeh, A.; Hassanshahi, G.; Salehi, M.; Ahmadabadi, BN.; Kennedy, D. (2011). Hepatitis B virus genotype, HBsAg mutations and co-infection with HCV in occult HBV infection. Clinics and Research in Hepatology and Gastroenterology, 35, 554-559
  8. Arababadi, MK.; Hassanshahi, G.; Pourfathollah, AA.; Zarandi, ER.; Kennedy, D. (2011 proof available) Post-Transfusion Occult Hepatitis B (OBI): A Global Challenge for blood recipients and health authorities. Hepatitis Monthly accepted.
  9. Arababadi, MK.; Pourfathollah, AA.; Jafarzadeh, A.; Hassanshahi, G.; Daneshmandi, S.; Shamsizadeh, A.; Kennedy, D. (2011). Non-association of IL-12 +1188 and IFN- +874 Polymorphisms with Cytokines Serum Level in Occult HBV Infected Patients. The Saudi Journal of Gastroenterology, 17, 30-5
  10. Arababadi, MK.; Pourfathollah, AA.; Jafarzadeh, A.; Hassanshahi, G.; Shamizadeh, A.; Ahmadabadi, BN.; Kennedy, D. (2011). The status of humoral immunity in occult HBV infection in south-eastern Iranian patients. Clinics and Research in Hepatology and Gastroenterology, 35, 309-314
  11. Arababadi, MK.; Abousaidi, H.; Pourfathollah, AA.; Daneshmandi, S.; Akbarpour, V.; Hakimi, H.; Kennedy, D. (2011). Polymorphisms within exon 9, but not intron 8, of the Vitamin D Receptor gene are associated with Asthma. Iranian Journal of Basic Medical Science, 14, 225-230
  12. Arababadi, MK.; Mohammadzadeh, A.; Kennedy, D.; Pourfathollah, AA. (2011). Polymorphisms within Fas gene are not associated with occult hepatitis B virus infection Hepatitis Monthly, 11, 23-26.
  13. Arababadi, MK.; Mosavi, R.; Khoramdel, H.; Yaghini, N.; Zarandi, ER.; Araste, M.; Pourali, R. Nekhei, Z.; Kennedy, D. (2010). Cytokine patterns after therapy with Anovex, Rebif, Betaferon and Cinnovex in relapsing–remitting multiple sclerosis Iranian patients. Biomarkers in Medicine, 4, 755-759
  14. Arababadi, MK.; Pourfathollah, AA.; Jafarzadeh, A.; Hassanshahi, G.; Mohit, M.; Hajghani, M.; Ahmadabadi, BN.; Kennedy, D. (2010). Evaluation of CCR5 expression on NK cells in Iranian patients with occult hepatitis B infection. LabMedicine, 41, 735-38
  15. Arababadi, MK.; Nosratabadi , R.; Salehabad, VA.; Shamsizadeh, A.; Mahmoodi, M,; Sayadi, AR.; Kennedy, D. (2010) Polymorphisms within Exon 9 but not intron 8 of the Vitamin D Receptor are associated with the nephropathic complication of type-2 diabetes. International Journal of Immunogenetics, 37, 493-7.
  16. Arababadi, MK.; Mohammadzadeh, A.; Ahmadabadi, BN.; Pourfathollah, AA.; and Kennedy, D. (2010). Are Fas ligand polymorphisms associated with occult HBV infection? LabMedicine, 41, 672-675
  17. Ebrahimi, H.; Soleimani, M.; Arababadi, MK.; Ahmadbeigi, N.; Hassanshahi, G.; Farjadfar, A.; Kennedy, D. (2010). An In Vitro Assay to Evaluate the Immunomodulatory Effects of Unrestricted Somatic Stem Cells. Iran. J. Immunol, 7, 30-8
  18. Papp, L.V.; Wang, J.; Kennedy, D.; Boucher, D.; Zhang, Y.; Gladyshev, V.N.; Singh, R.N.; Khanna, K.K. Functional characterization of alternatively spliced human SECISBP2 transcript variants. Nucleic Acids Res 2008, 36(22), 7192-206.
  19. Solomon, S.; Xu, Y.; Wang, B.; David, M. D.; Schubert, P.; Kennedy, D.; Schrader, J. W. Distinct structural features of caprin-1 mediate its interaction with G3BP-1 and its induction of phosphorylation of eukaryotic translation initiation factor 2alpha, entry to cytoplasmic stress granules, and selective interaction with a subset of mRNAs. Mol Cell Biol 2007, 27, 2324-42.
  20. Kim, M. M.; Wiederschain, D.; Kennedy, D.; Hansen, E.; Yuan, Z. M. Modulation of p53 and MDM2 activity by novel interaction with Ras-GAP binding proteins (G3BP). Oncogene 2007.
  21. Papp, L. V.; Lu, J.; Striebel, F.; Kennedy, D.; Holmgren, A.; Khanna, K. K. The redox state of SECIS binding protein 2 controls its localization and selenocysteine incorporation function. Mol Cell Biol 2006, 26, 4895-910.
  22. Moran-Jones, K.; Wayman, L.; Kennedy, D. D.; Reddel, R. R.; Sara, S.; Snee, M. J.; Smith, R. hnRNP A2, a potential ssDNA/RNA molecular adapter at the telomere. Nucleic Acids Res 2005, 33, 486-96.
  23. Kim, M. M.; Wiederschain, D.; Hansen, E.; Kennedy, D.; Yuan, Z. M. Estradiol-mediated upregulation of G3BPs results in functional inactivation of p53 in human breast cancer cells. American Association for Cancer Research 2005, 96 annual meeting, Ab5249.
  24. Whitchurch, C. B.; Leech, A. J.; Young, M. D.; Kennedy, D.; Sargent, J. L.; Bertrand, J. J.; Semmler, A. B.; Mellick, A. S.; Martin, P. R.; Alm, R. A.; Hobbs, M.; Beatson, S. A.; Huang, B.; Nguyen, L.; Commolli, J. C.; Engel, J. N.; Darzins, A.; Mattick, J. S. Characterization of a complex chemosensory signal transduction system which controls twitching motility in Pseudomonas aeruginosa. Mol Microbiol 2004, 52, 873-93.
  25. Irvine, K.; Stirling, R.; Hume, D.; Kennedy, D. Rasputin, more promiscuous than ever: a review of G3BP. Int J Dev Biol 2004, 48, 1065-77.
  26. Utama, B.; Hartmann, B.; Mattick, J.; Ru, K.; Wang, X. L.; Kennedy, D. Nrap, a novel nucleolar protein which interacts with B23/Nucleophosmin during ribosomal biogenesis. Faseb Journal 2003, 17, A180-A180.
  27. Bloomfield, K. L.; Osborne, S. A.; Kennedy, D. D.; Clarke, F. M.; Tonissen, K. F. Thioredoxin-mediated redox control of the transcription factor Sp1 and regulation of the thioredoxin gene promoter. Gene 2003, 319, 107-116.
  28. Kennedy, D.; Utama, B.; Ru, K.; Mattick, J. S. Isolation and characterization of a new nucleolar protein, Nrap, that is conserved from yeast to humans. Genes to Cells 2002, 7, 115-132.
  29. Jawerth, K.; French, J.; Stirling, R.; Turtle, C. J.; Hart, D. N. J.; Lopez, J. A.; Kennedy, D. G3BP and Breast Cancer Immunotherapy. Recent Advances in Inflamamation Research 2002, 3, 19-42.
  30. French, J.; Stirling, R.; Walsh, M.; Kennedy, H. D. The expression of Ras-GTPase Activating Protein SH3 domain-binding Proteins, G3BPs, in human breast cancers. Histochemical Journal 2002, 34, 223-231.
  31. Kennedy, D.; French, J.; Guitard, E.; Ru, K.; Tocque, B.; Mattick, J. Characterization of G3BPs: tissue specific expression, chromosomal localisation and rasGAP(120) binding studies. J Cell Biochem 2001, 84, 173-87.
  32. Urquhart, A. J.; Kennedy, D.; Gould, S. J.; Crane, D. I. Interaction of Pex5p, the Type 1 Peroxisome Targeting Signal Receptor, with the Peroxisomal Membrane Proteins Pex14p and Pex13p. Journal of Biological Chemistry 2000, 275, 4127-4136.
  33. Fitzgerald, J.; Kennedy, D.; Viseshakul, N.; Cohen, B. N.; Mattick, J.; Bateman, J. F.; Forsayeth, J. R. UNCL, the mammalian homologue of UNC-50, is an inner nuclear membrane RNA-binding protein. Brain Res 2000, 877, 110-23.
  34. Bolton, J. A.; Wood, S. A.; Kennedy, D.; Don, R. H.; Mattick, J. S. Retinoic acid-dependant upregulation of mouse folate receptor-alpha expression in embryonic stem cells, and conservation of alternative splicing. Gene 1999, 230, 215-224.
  35. Kennedy, D.; Colombo, P.; Ramsdale, T.; Costa, M. A.; Duro, G.; Izzo, v.; Salvadori, S.; Guerrini, R.; Cochiara, R.; Mirisola, M. G.; Wood, S. A.; Geraci, D. Identification of an immunodominant IgE epitope of the Parietaria judaica major allergen. J. Immunology 1998, 160, 2780-2785.
  36. French, J.; Kennedy, D. Trawling for genes: A case for computation in biochemistry. Chemistry in Australia 1998, 65, 37-39.
  37. Kennedy, D.; Wood, S. A.; Ramsdale, T.; Tam, P. P.; Steiner, K. A.; Mattick, J. S. Identification of a mouse orthologue of the human ras-GAP-SH3-domain binding protein and structural confirmation that these proteins contain an RNA recognition motif. Biomed Pept Proteins Nucleic Acids 1997, 2, 93-9.
  38. Kennedy, D.; Wood, S. A.; Ramsdale, T.; Tam, P. P.; Steiner, K. A.; Mattick, J. S. Identification of a mouse orthologue of the human ras-GAP-SH3-domain binding protein and structural confirmation that these proteins contain an RNA recognition motif. Biomed Pept Proteins Nucleic Acids 1996, 2, 93-9.
  39. Kennedy, D.; Ramsdale, T.; Mattick, J.; Little, M. An RNA recognition motif in Wilms' tumour protein WT1 revealed by structural modelling. Nature Genetics 1996, 12, 329-331.
  40. Costa, M. A.; Colombo, P.; Izzo, V.; Kennedy, H. D.; Venturella, S.; Cocchiara, R.; Mistrello, G.; Falagiani, P.; Geraci, D. cDNA cloning, expression and primary structure of Par j I, a major allergen of Parietaria Judaica pollen. FEBS. Letters 1994, 341, 182-186.

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