Associate Professor Chris Barclay

B Science, M Science (Hons), PhD

Associate Professor

Contact details for Associate Professor Chris Barclay

Research expertise

• Energetics of skeletal and cardiac muscle
• Muscle mechanics
• Muscle efficiency
• Cross-bridge models of muscle contraction
• Modelling of O₂ diffusion

Current teaching areas

• Health Group Honours convenor
  
• Mathematics and Statistics for Clinical Sciences

Selected publications

• Barclay, C. J., Woledge, R. C. and Curtin, N. A. (2009). Effects of UCP3 genotype, temperature and muscle fibre type on energy turnover of resting mouse skeletal muscle. Pflügers Archiv  457, 857-864.
• Barclay, C. J. (2008). Getting energy to where it is required is a problem in the failing heart. Journal of Physiology  586, 5037-5038.
• Barclay, C. J., Lichtwark, G. A. and Curtin, N. A. (2008). The energetic cost of activation in mouse fast-twitch muscle is the same whether measured using reduced filament overlap or N-benzyl-p-toluenesulphonamide. Acta Physiologica  193, 381-391.
• Loiselle, D. S., Crampin, E. J., Niederer, S. A., Smith, N. P. and Barclay, C. J. (2008). Energetic consequences of mechanical loads. Progress in Biophysics and Molecular Biology  97, 348-366.
• Barclay, C. J., Woledge, R. C. and Curtin, N. A. (2007). Energy turnover for Ca²⁺ cycling in skeletal muscle. Journal of Muscle Research and Cell Motility 28, 259-274.
• Barclay, C. J. and Lichtwark, G. A. (2007). The mechanics of mouse skeletal muscle when shortening during relaxation. Journal of Biomechanics 40, 3121-3129.
• Barclay, C. J. and Loiselle, D. S. (2007). Can activation account for 80% of skeletal muscle energy use during isometric contraction? American Journal of Physiology Cell Physiology 292, C612.
• Widén, C. and Barclay, C. J. (2006). ATP-splitting by half the cross-bridges can explain the twitch energetics of mouse papillary muscle. Journal of Physiology 573, 5-15.
• Barclay, C. J. (2005). Modelling diffusive O₂ supply to isolated preparations of mammalian skeletal and cardiac muscle. Journal of Muscle Research and Cell Motility 26, 225-235.
• Barclay, C. J. (2005). The maximum contractile filament movement per ATP split in muscle is 1.3 nm not 13 nm.  International Journal of Biological Macromolecules. 37, 154-155.
• Extended list of publications (PDF 24k)