Griffith University

Lecturer

Contact details for Dr Andrew Battle

Responsibilities

• 3025PHM Chemical Pharmacology II (Convenor)
• 3026PHM Pharmaceutical Analysis (Convenor)

Research expertise

• Drug design and delivery
• Mechanosensitive ion channels
• Electrophysiology

Recent research grants

• Battle, A., Dukie, S., Nirthanan, N., & Brown, C. (2012). Studying stretch active ion channel properties using the patch- and pressure-clamp. Griffith University Research Infrastructure Program - $50,000.
• Battle, A., Martinac, B., & Cornell, B. (2012). Multidrug resistance - targeting membrane effects on bacterial mechanosensitive (MS) channels. Griffith University New Research Grant Scheme - $13,576.
• Battle, A., & Martinac, B. The interplay between membrane environment, amphipaths and mechanosensitive channels on Ca²⁺ signalling in cardiac myocytes and cardiac arrhythmias. Griffith University Molecular Basis of Disease Program - $8,000.
• Martinac, B., Hankamer, B., & Battle, A. (2010-2012). MS Channel nanovalves for controlled drug delivery from liposomes. NHMRC.

Recent publications

• Grage, S. L., Keleshian, A. M., Turdzeladze, T., Battle, A. R., Tay, W. C., May, R. P., ... Martinac, B. (2011). Bilayer-mediated clustering and functional interaction of MscL channels. Biophysical Journal, 100(5), 1252-1260.
• Battle, A. R., Bond, A. M., Chow, A., Daniels, D. P., Deacon, G. B., Hambley, T. W., ... Wang, J. (2010). Syntheses and structures of N-polyfluorophenyl- and N,N'-bis(polyfluorophenyl)ethane-1,2-diaminato(1- or 2-)platinum(II) complexes. Journal of Fluorine Chemistry, 131(11), 1229-1236.
• Börngen, K., Battle, A. R., Möker, N., Morbach, S., Marin, K., Martinac, B., & Krämer, R. (2010). The properties and contribution of the Corynebacterium glutamicum MscS variant to fine-tuning of osmotic adaptation. BBA-Biomembranes, 1798(11), 2141-2149.
• Romantsov, T., Battle, A. R., Hendel, J., Martinac, B., & Wood, J. M. (2010). Protein localization in Escherichia coli cells: comparison of the cytoplasmic membrane proteins ProP, LacY, ProW, AqpZ, MscS, and MscL. Journal of Bacteriology, 192(4), 912-924.
• Battle, A. R., Petrov, E., Pal, P., & Martinac, B. (2009). Rapid and improved reconstitution of bacterial mechanosensitive ion channel proteins MscS and MscL into liposomes using a modified sucrose method. FEBS Letters, 583(2), 407-412.
• Battle, A. R., Valenzuela, S. M., Mechler, A., Nichols, R. J., Praporski, S., ... Martin, D. K. (2009). Novel engineered ion channel provides controllable ion permeability for polyelectrolyte microcapsule coated with a lipid membrane. Advanced Functional Materials, 19(2), 201-208.
• Cornell, B., Krishnamurthy, V., Luk, K. Y., Valenzuela, S., di Maio, I., Battle, A. R., ... Martin, D. K. (2007). Gramicidin ion channel based nano-biosensors: construction, stochastic models and statistical detection algorithms. IEEE Sensors Journal, 7(9), 1281-1288.
• Battle, A. R., Edwards, P. G., Haigh, R., Hibbs, D. E., Li, D. M., Liddiard, S. M., & Newman, P. D. (2007). Synthesis and characterization of Iron(II) complexes of 10- and 11-membered triphosphomacrocycles. Organometallics, 26(2), 377-386.
• Belusoff, M., Battle, A. R., Graham, B., & Spiccia, L. (2007). Synthesis, structure and hydrolytic properties of Copper(II) complexes of asymmetrically N-functionalized 1,4,7-triazacyclonoanes. Polyhedron, 26, 344-355.
• Battle, A. R., & Martin , L. L. (2006). 1-Undecyl-4,7-1-azoniatricyclo[5.2.1.0^4,10]-decane iodide. Acta Crystallographica Section E, 62(9), o4089-o4091.