Griffith University

FRACP, PhD, MSpM, MBBS (Hons-1)

Gold Coast Health Service District - Director of Cardiology and Cardiac Services

Contact details for Professor Rohan Jayasinghe

Biography

Professor Jayasinghe graduated from Sydney University Medical Faculty with First Class Honours and earned MSpM degree from University of New South Wales and a PhD in Cardiology from University of New South Wales. He completed Cardiology training at Westmead Hospital and earned fellowships in Interventional Cardiology from John Hunter Hospital, Newcastle Australia and Beth Israel Hospital New York United States of America.

He currently holds the positions of Professor of Cardiology for Griffith University since 2006 and Director of Cardiology and Cardiac Services at the Gold Coast Hospital since 2006. Founder Co-Director of APIA conferences in Newcastle (2005) and Sydney (2006). He is also the co-inventor of JT percutaneous mitral valve replacement technology and member of the Working Group on Acute Cardiac Care of the European Society for Cardiology.

Research interests

• Interventional cardiology - interventional device development
• Heart failure - cardiovascular clinical trials
• Pulmonary hypertension - cardiac rehabilitation - mental illness and cardiovascular disease
• Cardiovascular genetics - indigenous cardiovascular health

Current research projects

• CHAMPION PCI Trial (R Jayasinghe and D Bhatt)
• Establishment of the Vascular, Metabolic and Lipid Research Core Group of the Gold Coast Hospital (Laurie Howes, Karam Kostner, Ian Hamilton-Craig, Maartan Kamp and Rohan Jayasinghe)
• Gold Coast Cardiovascular DNA Bank
  
• B Vs C study - Bisoprolol Vs Carvedilol comparative efficacy study in heart failure patients - prospective & retrospective (Rohan Jayasinghe and Dr Frank Jia)
• Precise Registry - Premier device for PFO closure
• GOHARD IVUS study - to ascertain coronary plaque regression using IVUS in diabetic patients - a randomized controlled trial using Niacepan Vs placebo (R Jayasinghe and K Kostner)
• TIMACs study
  
• ReoPro vs Integrillin in Acute MI comparative study
• Early ACS study
• Australian and New Zealand registry into stent thrombosis (ANTS study)
• AVVEROS study
• TRPS - TIMI 50 study (Phase 3 clinical trial)
• TASLY study (Phase 2 clinical trial - T 89)
• BEACON registry - Biomatrixx - biolimus eluting stent
• Q Heart Survey - A comprehensive survey into identifying the gaps in the treatment of common cardiac conditions in the community, primary care setting (R Jayasinghe and Dr K Kisana)
  
• RINCAP study - RCT comparing best hydration and n acetyl cystine with sodium bicarbonate in the prevention of contrast nephropathy during catheterization (Rohan Jayasinghe and Thomas Titus)
• DNA analysis of patients with PFO & Migrain (Rohan Jayasinghe, Naylin Bissessor, and Lynn Griffiths)
• CORAL study comparing stenting with best medical management of significant renal artery stenosis: international, multi-centre RCT (Rohan Jayasinghe, Balaji Hiremagular, and Thomas Snow)
• ACTION study - Integrillin Vs Reo Pro in Acute Coronary Intervention
  

Current grants

• "Cardiovascular DNA Bank", Gold Coast Hospital Foundation Grant - $4,500
• "Cardiovascular DNA Bank", Bond University Research Grant Scheme, $60,000 (Rohan Jayasinghe and Angela Van Daal)
• "Cardiovascular DNA Bank", Bond Univesity Academic Research Grant, $20,000

Publications

Books

• Jayasinghe R. (2004) One Heart-One Life: a scientific guide to the complete mind-body renewal for heart health ? Revere Life publishers, released in New York (200 pages)Rohan Jayasinghe. (2003) At a varsity far away ? An anthology of poems (Sinhalese and English)
• Jayasinghe R. (2002, 2003, 2006, 2008) Mastering the Medical Long Case, (Examination aid to Internal Medicine) MacLennan and Petty Medical Publishers (Sydney, Philadelphia, London), Elsevier Australia (300 pages)Rohan Jayasinghe. (2001-2002) An Aid to the Medical Long Case, Textbook of practical internal medicine. Century Scientific. Best Seller (350 pages)
• Jayasinghe R. (2000) Sport Medicine (a textbook), Godage publishers (200 pages)

Refereed journal articles

• Bissessor N, Shen Wee Y, Jayasinghe R, Zeng I, Lowe B, Kolbe J, Ellyet K, Kerr A, White H, Stewart RY. (2010) Complimentary roles for N-terminal pro-B-type natriuretic peptide and spirometry to assess functional capacity in patients with complex mixed heart valve disease. Kardiologia Polska. 68(1): 1-10
• Nasir A, Batra R, Jayasinghe RN. (2010) A Clinical Review of Implantable Cardioverter Defibrillators and Bi-Ventricular Pacemakers at one Institute. Australasian Medical Journal. 1(1):23-27
• Bissessor N, Shanahan L, Wee YS, Stewart R, Lowe B, Kerr A, Zeng I, Jayasinghe R, White H. (2010) The role of natriuretic peptides in patients with chronic complex (mixed or multiple) heart valve disease. Congestive Heart Failure. 16(2):50-54
• Jayasinghe R, Kostner K. (2009) Lp(a) and coronary artery disease - Rule of Engagement - How to Measure and how to treat. South African Medical Journal. 99(7):502-504
• Bissessor N, Stewart R, Wee YS, Zeng I, Jayasinghe R, Howes L, Kolbe J, Kerr A, Lowe B, Ellyett K, White H. (2009) Complex Valve Disease: Pre-Surgical Functional Capacity Evaluation Using Peak Oxygen Consumption. Journal of Heart Valve Disease. 18(5):554-561
  
• Jayasinghe SR, Jayasinghe SH. (2009) Variant metabolic risk factor profile leading to premature coronary disease: time to define the syndrome of accelerated atherocoronary metabolic syndrome in Asian Indians. Singapore Medical Journal. 50(10):949-955
• Jayasinghe SR, Varghese P, Rajendran S. (2008) A Universal Classification System for Chronic Total Occlusions. Journal of Invasive Cardiology. 20(6):302-304
• Jayasinghe SR, Jayasinghe SH. (2008) AAMS - A Distinct Syndrome and an Emerging Epidemic. Indian Heart Journal. 60 Suppl B: B48-B51
• Jayasinghe SR, Thompson AG, Razak S. (2007) Cardiac arrest and chewing gum - an unfortunate combination. Medical Journal of Australia. 187:(11/12):635
• Jayasinghe SR, Hiew C. (2005) Contrast induced nephropathy - genesis, prevention and treatment. Australasian Heart Journal. 1(1):34-44 (Review)
• Jayasinghe SR, Mayalabathula S, Thambar S. (2005) Cytokines, genes and stem cells in anti-ischaemia therapy. Australasian Heart Journal. 1(1):19-26 (Review)
• Jayasinghe SR, Diu P. (2005) BNP levels and contrast nephropathy in patients with impaired renal function undergoing cardiac catheterization. Australasian Heart Journal. 1(1):12-18
• Jayasinghe SR, Wong E, Patel S. (2005) Transient global amnesia following coronary catheterization. Internal Medicine Journal. 35(7): 435-436 (Review)
• Jayasinghe SR. (2004) A new tool for the assessment of the psychological state of post myocardial infarction patients. Cardiology/Kardiologia. 13(2):90-93
• Jayasinghe SR, Kovoor PK. (2002) Drugs and Long QT syndrome - (A Review). Australian Prescriber. 6:55-63
• Jayasinghe SR. (2004) Yoga in Cardiac Health - (A Review). European Journal of Cardiac Rehabilitation and Prevention. 14(2):98-105

Other published articles

• Jayasinghe R. (2008) Spirometry and N-terminal-pro-B-type natriuretic peptide combined predict impaired functional capacity in patients with chronic rheumatic heart disease - The Cardiac Society of Australia and New Zealand, New Zealand Annual Scientific Meeting
• Bissessor N, Stewart RAH, Kerr AAH, Mak B, Zeng I, White H, Howes L, Jayasinghe R. (2008) NYHA functional class assessment in chronic complex mixed valve disease (MVD) using cardiopulmonary exercise testing (CPEX)
• Jayasinghe R, Bissessor N. (2008) Efficacy of transcatheter patent foramen ovale (PFO) closure in the management of migrainous headache. CCT2008 Complex Catheter Therapeutics Kobe Japan
• Jayasinghe R, Bissessor N. (2008) Comparison of the safety and efficacy of two PFO closure devices. CCT2008 Complex Catheter Therapeutics Kobe Japan
• Jayasinghe R, Bissessor N. (2008) Efficacy Of Transcatheter Patent Foramen Ovale (PFO) Closure In The Management Of Migrainous Headache. Cardiac Revascularization Therapies (CRT) Washington DC, CRT
• Jayasinghe R, Bissessor N. (2008) NtproBNP Predicts Impaired Functional Capacity In Chronic Mixed Heart Valve Disease (MVD) - Cardiac Revascularization Therapies (CRT) Washington DC, CRT
• Jayasinghe R, Bissessor N. (2008) Comparison of The Safety And Efficacy Of Two PFO Closure Devices in a non-cardiac surgery centre- Cardiac Revascularization Therapies (CRT) Washington DC, CRT
• Jayasinghe R, Bissessor N, et al. (2007) Comparing Cardiopulmonary Exercise Testing with Standard Exercise Testing in Mixed Valve Disease - Annual Scientific Sessions of the Cardiac Society of Australia and NZ - Christchurch - NZ - August
• Jayasinghe R, Bissessor N, Rahman, Essack. (2007) PFO closure and its effect on migraine headaches - a single centre experience Annual Scientific Sessions of the Cardiac Society of Australia and NZ - Christchurch - NZ - August
• Jayasinghe R. (2005) A Classification System for Chronic Total Occlusions of Coronary Arteries - Asia Pacific Interventional Advances Conference - November/December, Newcastle
• Mylabathula S, Jayasinghe SR, Thambar S. (2005) Calicification and tumor genesis after intracardiac stem cell injection - Follow up study - Submitted to the Scientific Sessions of the AHA, Chicago
• Mylabathula S, Jayasinghe SR. (2005) Long Term Outlook of a "Stent and Retrieve (provisional stenting)" Bi-furcation Intervention - Presented at the Euro PCR - May Paris
• Mylabathula S, Jayasinghe SR. (2005) Role of IVUS Vs Pressure Wire in determining coronary intervention - a study, submitted to ESC scientific sessions - Stockholm
• Diu P, Jayasinghe SR. (2005) BNP in contrast nephropathy - the BRACA study - Presented at The Scientific Meeting of the RACP - May Wellington NZ
• Mylabathula S, Jayasinghe SR. (2005) Delays and efficient delivery of primary angioplasty - a review of confounding issues- Accepted for Presented at CSANZ August Perth
• Mylabathula S, Jayasinghe SR. (2005) Modified - Newcastle Crush - a novel techniques for bifurcation stenting - A case series for short and long term efficacy - Presented at Cardiac Society of Australia and New Zealand ( CSANZ) August Perth
• Myalabathula S, Jayasinghe SR. (2004) Investigation into the fundamental delays associated with the provision of primary percutaneous revascularization for acute myocardial infarction - presented at the European Society of Cardiology acute Cardiac Care summit Rome, 18 - 20 October
• Sivagangabalan G, Jayasinghe SR. (2003) Prediction of the type of myocardial infarction using the Jayasinghe formula based on the coronary risk factor profile- poster presented at: Scientific sessions of the Cardiac Society of Australia and New Zealand, Adelaide August
• Jayasinghe SR, Denniss ARD. (2002) Phase 2 cardiac rehabilitation and serum lipid profile in post myocardial infarction patients - Abstract presented at the World Congress on Cardiology, Satellite conference on cardiac rehabilitation, Sydney May
• Jayasinghe SR. (2001) Indian sub-continental ethnicity, an independent risk factor for severe coronary artery disease?  4th International Congress on Coronary Artery Disease - From Prevention to Intervention, Prague, October
• Jayasinghe SR, Garlick D. (2000) Physical exercise and coronary artery disease revisited-a case control study, presented at the International Congress on Sports Medicine, Sports Science and Physical Education, Brisbane