BBehSc, BSc (Hons), PhD
Lecturer
First Year Advisor
Contact details for Dr Andrew Pearson
Research expertise
- Organic chemistry
- Carbohydrate chemistry
Current teaching areas
- Essentials of Chemistry and Physics
- Chemistry in Biological Systems
Publications
- Pearson, A. G.; Peak, I. R.; Wilson, J. C.; Grice, I. D. Synthesis of a novel pentasaccharide core component from the lipooligosaccharide of Moraxella catarrhalis. Carbohydrate Research 2011, 346 (17), 2805-2811.
- Pearson, A. G., Kiefel, M. J., Ferro, V. & von Itzstein, M. Synthesis of simple heparanase substrates. Organic & Biomolecular Chemistry 2011, 9 (12), 4614-4625.
- Abbenante, G.; Becker, B.; Blanc, S.; Clark, C.; Condie, G.; Fraser, G.; Grathwhol, M.; Halliday, J.; Henderson, S.; Lam, A.; Liu, L.; Mann, M.; Muldoon, C.; Pearson, A.; Premraj, R.; Ramsdale, T.; Rosetti, T.; Schafer, K.; Le Thanh, G.; Tometzki, G.; Vari, F.; Rossetti, T.; Verquin, G.; Waanders, J.; West, M.; Wimmer, N.; Yau, A.; Zuegg, J.; Meutermans, W. Biological diversity from a structurally diverse library: systematically scanning conformational space using a pyranose scaffold. Journal of Medicinal Chemistry 2010, 53 (15), 5576-5586.
- Thanh, G. L.; Abbenante, G.; Adamson, G.; Becker, B.; Clark, C.; Condie, G.; Falzun, T.; Grathwohl, M.; Gupta, P.; Hanson, M.; Huynh, N.; Katavic, P.; Kuipers, K.; Lam, A.; Liu, L.; Mann, M.; Mason, J.; McKeveney, D.; Muldoon, C.; Pearson, A.; Rajaratnam, P.; Ryan, S.; Tometzki, G.; Verquin, G.; Waanders, J.; West, M.; Wilcox, N.; Wimmer, N.; Yau, A.; Zuegg, J.; Meutermans, W. A versatile synthetic approach toward diversity libraries using monosaccharide scaffolds. Journal of Organic Chemistry 2010, 75 (1), 197-203.
- Pearson, A. G.; Kiefel, M. J.; Ferro, V.; von Itzstein, M. Towards the synthesis of aryl glucuronides as potential heparanase probes. An interesting outcome in the glycosidation of glucuronic acid with 4-hydroxycinnamic acid. Carbohydrate Research 2005, 340 (13), 2077-2085.
- Meharenna, Y. T.; Li, H. Y.; Hawkes, D. B.; Pearson, A. G.; De Voss, J.; Poulos, T. L. Crystal structure of P450cin in a complex with its substrate, 1,8-cineole, a close structural homologue to D-camphor, the substrate for P450cam. Biochemistry 2004, 43 (29), 9487-9494.
- Davies, C.; Witham, K.; Scott, J. R.; Pearson, A.; De Voss, J. J.; Graham, S. E.; Gillam, E. M. J. Assessment of arginine 97 and lysine 72 as determinants of substrate specificity in cytochrome P450 2C9 (CYP2C9). Drug Metabolism and Disposition 2004, 32 (4), 431-436.