Griffith University

PhD

Lecturer

Contact details for Dr Andrew Bulmer

Research expertise

• Role of antioxidants and oxidative stress in cardiovascular disease
• Use of ultrasound for heart (echocardiography) visualisation
• Anti-mutagenic and anti-carcinogenic effects of bilirubin/biliverdin; effects of altered heme oxygenase gene expression on carcinogenesis/tumorigenesis
• Pharmacokinetics and hepatic metabolism of therapeutics
• Environmental stress (ultra-endurance exercise; breath-hold diving; high altitude exposure)/gene expression and inflammation

Current teaching areas

• Physiology/Pathophysiology

Publications 

• Boon, A-C., Hawkins, C.L., Bisht, K., Coombes J.S., Bakrania, B., Wagner, K-H., Bulmer, A.C. Reduced circulating oxidised LDL is associated with hypocholesterolemia and enhanced thiol status in Gilbert's syndrome, Free Radical Biology and Medicine, in press.
• Bulmer, A.C., Coombes, J.C., Blanchfield, J.T., Toth, I., Fassett, R. Taylor, S.M. (2011) Bile pigment phamacokinetics and absorption in the rat: therapeutic potential for enteral administration. British Journal of Pharmacology, 164(7):1857-70.
• Bisht, K. Wagner, K-H, Bulmer A.C.  (2010) Curcumin, resveratrol and flavonoids as anti-inflammatory, cyto- and DNA-protective dietary compounds. Toxicology, 278(1):88-100.
  
• Reichhold, S., Neubauer, O., Bulmer, A.C. and Wagner K-H. (2009). Effects of ultra-endurance exercise on markers of DNA damage. Mutation Research – Reviews in Mutation Research 682, 28-38.
• Bulmer, A.C., Blanchfield, J.T., Toth, I., Fassett, R.G. and Coombes J.S. (2008). Improved resistance to serum oxidation in Gilbert's syndrome: A mechanism for cardiovascular protection. Atherosclerosis 199, (2), 390-6.
• Bulmer, A.C., Blanchfield, J.T., Coombes, J.S. and Toth, I. (2008). In vitro permeability and metabolic stability of bile pigments and the effects of hydrophilic and lipophilic modification of biliverdin. Bioorganic and Medicinal Chemistry 16, (7), 3616-25.
• Morgan, M., Bulmer, A.C., Woodruff, T.M., Proctor, L.M., Williams, H.M., Stocks, S.Z., Pollitt, S., Taylor, S.M. and Shiels, I.A. (2008). Pharmacokinetics of a Small Molecule C5a Receptor Antagonist in the Rat after Different Sites of Enteral Administration. European Journal of Pharmaceutical Sciences 33, (4-5), 390-8.
• Bulmer, A.C., Coombes, J. S., Sharman, J. and Stewart, I.B. (2008). Effects of maximal static apnea on antioxidant defenses in trained free divers. Medicine and Science in Sports and Exercise 40, (7), 1307-13.
• Bulmer, A.C., Ried, K., Blanchfield, J.T. and Wagner, K-H. (2008). The anti-mutagenic properties of bile pigments. Mutation Research-Reviews in Mutation Research 658, 28-41.
• Bulmer, A.C., Ried, K, Blanchfield, J., Coombes, J.S., Toth, I. and Wagner, K-H. (2007). The anti-mutagenic and antioxidant effects of bile pigments in the Ames Salmonella test. Mutation Research-Genetic Toxicology and Environmental Mutagenesis 629, 122-132.
• Stewart, I. B., Bulmer A.C., Sharman, J.E. and Ridgway, L. (2005). Arterial Oxygen desaturation kinetics during apnea. Medicine and Science in Sports and Exercise 37, (11), 1871–1876.
• Bulmer, A.C. and Coombes, J.S. (2004). Optimising exercise training in peripheral arterial disease. Sports Medicine 34, (14), 983–1003.